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Kick the butt: Smoking changes lung cells, readies them for cancer

Chronic exposure to cigarette smoke can change lung cells over time, making them more vulnerable to disease and priming them to develop cancer, say US researchers. The report in the journal Cancer Cell is based on lab experiments on lung cells that were exposed to chronic cigarette smoke – the equivalent of a person smoking for 20 to 30 years. After about 10 days, the cells began to change their gene expression, a process known as epigenetic change. It took 10 months before these changes built up enough to boost…

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Defective Brain Cells Are Spreading Alzheimer’s and Parkinson’s

Brain is the most important organ of the human body yet most of its functioning is still unknown to doctors and scientists. We humans use merely five per cent of the brain’s total functioning throughout our life. The full potential of a human brain’s working has yet not been completely figured out. Neurons are the building blocks of the nervous system which includes the brain and the spinal cord. Neurons normally don’t reproduce or replace themselves, so when they become damaged or die they cannot be replaced by the body…

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Doctors arm immune system to fight cervical cancer cells

Doctors were bewildered when they went through the case sheet of a woman who was diagnosed with advanced cervical cancer nearly 10 years ago. More than a year after a full dose of radiotherapy, cancerhad spread to the lung. By then the disease should have claimed her life. Yet, she continues to visit them for periodic checks. Tests show she is free of the ailment. When diagnosed with cancer, her oncologist at the Cancer Institute (WIA) here had included her name for an experimental treatment – immunotherapy. Rather than directly…

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Cocktail of diabetes and hypertension drugs kills cancer cells

A combination of drugs for diabetes and hypertension may offer an effective new way to combat cancer, suggests a new research. In their experiments, the researchers found that the combination of the diabetes drug metformin and the antihypertensive drug syrosingopine drives cancer cells to programmed “suicide”. “We have been able to show that the two known drugs lead to more profound effects on cancer cell proliferation than each drug alone,” said study first author Don Benjamin from the University of Basel in Switzerland. “The data from this study support the…

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Laser therapy with deep-sea drug kills prostate cancer cells

A non-surgical treatment for lowrisk prostate cancer, in which doctors inject a light-sensitive drug derived from deep-sea bacteria into a patient’s bloodstream, was shown in a trial to kill cancer cells without destroying healthy tissue. Results of a trial in 413 patients showed that the drug, which is activated with a laser to destroy tumour tissue in the prostate, was so effective that half the patients went into remission, compared with 13.5% in a control group.”These results are excellent news for men with early localised prostate cancer, offering a treatment…

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Bask in the sunlight to energise your immune cells

Bask in the sunlight to energise your immune cells Apart from helping for a healthier living by producing vitamin D, getting some sunlight may also energise T cells — immune cells — that play a central role in fighting infections in the human body, a study has found. “We all know sunlight provides vitamin D, which is suggested to have an impact on immunity, among other things. But what we found is a completely separate role of sunlight on immunity,” said Gerard Ahern, Associate Professor at the Georgetown University in…

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