​Why cancer treatments cause collateral damage in kids

When exposed to cancer treatment like chemotherapyand radiation, brain and heart tissues in very young children are more prone to apoptosis or programmed cell death, researchers said. Apoptosis, in which molecular signals order cells to self-destruct, plays an important role in deciding the “fate” of a developing cell. These toxic treatment stressors put young children at high risk for developing severe, long-lasting impairments in their brain, heart, the study said. But active apoptosis in the early brain “also sets the stage for extremely high sensitivity to any type of damage…

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