Novel treatment for cancer: Immunotherapy trials show promise in curing the disease

In the winter of 2013, Sue Scott, then 36, had already planned her own funeral. Her cervical cancer was spreading fast. Multiple rounds of chemotherapy, radiation and surgery had all failed. Tumours were invading her liver and colon, and squeezing her ureters. Her last chance was to enroll in an experimental trial in which doctors were trying to partially replace patients’ immune systems with T-cells that would specifically attack cancers caused by the human papillomavirus (HPV), a common sexually transmitted infection. Within a few months, her tumours completely disappeared. This…

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Indian Council of Medical Research Will Implement UN Standards On Clinical Trials

The Indian Council of Medical Research (ICMR) along with some of the leading healthcare bodies and other trusts has decided to adopt UN health agency’s recommendations to register and publicly disclose results of all clinical trials they fund or support. The participating bodies have all agreed to develop and implement policies within the next 12 months that require all trials they fund, co-fund, sponsor or support to be registered in a publicly-available registry. They also agreed that all results would be disclosed within specified timeframes on the registry or by…

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Older women with breast cancer still left out of medical trials

Older women are still underrepresented in medical trials evaluating treatments for breast cancer, according to a new study. Of three different types of trials evaluated by researchers, only one had an increase in enrollment of older women with breast cancer between 1985 and 2012. The other two had decreases. Seeing how older people react to cancer therapies “is crucial to inform decision-making and to optimally serve patients’ medical, emotional, and functional needs,” the authors of the study write in the Journal of Clinical Oncology, online December 19. “As physicians and…

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Older women with breast cancer still left out of medical trials

Older women are still underrepresented in medical trials evaluating treatments for breast cancer, according to a new study. Of three different types of trials evaluated by researchers, only one had an increase in enrollment of older women with breast cancer between 1985 and 2012. The other two had decreases. Seeing how older people react to cancer therapies “is crucial to inform decision-making and to optimally serve patients’ medical, emotional, and functional needs,” the authors of the study write in the Journal of Clinical Oncology, online December 19. “As physicians and…

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Austrian biotech plans Zika vaccine clinical trials in 12 months

An Austrian biotech company working with the Institut Pasteur said on Tuesday it planned to start clinical trials with an experimental Zika vaccine in the next 12 months, marking a further acceleration of research in the field. Themis Bioscience has signed a licence deal with the French research institute giving it extensive rights to the Zika vaccine candidate, which is based on established measles vaccine technology. More than a dozen small biotech firms and other organisations are working on vaccines against mosquito-borne Zika, which has been linked to birth defects…

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