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Binge drinking affects male and female brains differently, here’s why

While binge drinking affects the health of both males and females, the effect of gene expression in an area of the brain linked to addiction was found to be different, finds a new study. Repeated binge drinking was found to significantly alter molecular pathways in the nucleus accumbens — a region of the brain linked to addiction. But, in females, the genes linked to hormone signalling and immune function are altered, whereas in males genes related to nerve signalling are affected. The study has significant implications for the treatment of alcohol use…

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Insulin can boost your immune system, here’s how

Insulin, a peptide hormone produced by beta cells of the pancreatic islets, boosts immune health, according to a new study. Toronto General Hospital Research Institute (TGHRI) scientists have identified a specific insulin signalling pathway that, when activated, revs up the response of T cells in the immune system to divide rapidly and secrete cytokines, chemical messenger proteins that activate the rest of the immune system. A fast and effective immune response protects us against disease and life-threatening infections by destroying infected cells or microbes, while a wrong or inefficient one can…

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Here’s how heart diseases affect men and women differently. Find out if you’re at risk

Heart diseases have emerged as the leading cause for fatalities in men and women world over and also in India. The risk of heart diseases to both sexes is grave, but heart diseases affect men and women differently. Over one crore annual deaths are reported in India and cardiovascular diseases (CVD) cause 20.3% deaths in men and 16.9 percent deaths in women. Despite having a lower mortality rate than men, reports have often suggested that women are more at risk of CVD related deaths. Another Indian study reports that the incidence…

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Cancer rarely affects elephants, here’s the real reason behind it

Researchers have identified a “zombie” gene that protects elephants from cancer, a finding that may pave the way for a new treatment for humans. Globally, nearly 1 in 6 human deaths occur due to cancer, whereas less than 5% of captive elephants — who also live for about 70 years, and have about 100 times as many potentially cancerous cells as humans — die of the disease. Humans and elephants have one copy of the master tumour suppressor gene p53, which recognises unrepaired DNA damage — a precursor of cancer and…

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Why Do We Crave Alcohol? Here’s The Answer

Most people like occasional drinking or what’s called as social drinking, while some like binge-drinking on a daily basis. Some people are able to enjoy alcohol in moderation; others can’t seem to get enough of it. If you are in that stage when you need a drink or two to end your day with, it may mean that you crave alcohol. However, if you struggle to stop after one or two drinks, chances are you may be dealing with intense alcohol cravings. Why do we crave alcohol? What are the…

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Chronotherapy Could Make Cancer Treatments More Effective, Here’s How

Chi Van Dang generally declines to discuss the science that made him famous. A leading authority on cancer metabolism, he routinely is asked to speak about how tumors reprogram biochemical pathways to help them slurp up nutrients and how disrupting these noxious adaptations could be a powerful approach to treating cancer. Instead of doing so, Dang uses his soapbox at every research meeting, lecture and blue-ribbon panel to advocate for something else: a simple yet radical tweak to how oncologists administer cancer drugs. The approach, known as chronotherapy, involves timing…

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